By E3 ubiquitin ligases can be recognized and degraded by th
By E3 ubiquitin ligases can be recognized and degraded by the 26S proteasome, a...
In some cell lines and higher doses of BEZ235 may overcome t
In some cell lines and higher doses of BEZ235 may overcome the negative feedback...
Electropositive regions along with moderate section in hit c
Electropositive regions along with moderate section in hit compounds demonstrates that these regions can...
Degraded by the proteasome and treatment of HeLa cells with
Degraded by the proteasome and treatment of HeLa cells with MG-132 resulted in accumulation...
Studies of ours suggest that TKI-dependent combination thera
Studies of ours suggest that TKI-dependent combination therapy likely represents a potentially useful approach...
While this result is not fully explaining the extraordinary
While this result is not fully explaining the extraordinary difference in binding properties it...
This series named AP5055 and AP5258 produced a significant <
This series named AP5055 and AP5258 produced a AZD1152-HQPA significant inhibition of foam cells...
Interferon Regulatory Factor was able to restore MHC-1 expre
Interferon Regulatory Factor was able to restore MHC-1 expression and cellular immune complex formation...
Increased SERCA-2a connexin pPLB expression may occur as a r
Increased SERCA-2a connexin pPLB expression may occur as a result of lower myocardial UPS...
Aberrant methylation of CGIs in or near the promoter region
Aberrant methylation of CGIs in or near the promoter region of tumour suppressor genes...