Product Name :
CPDA inhibitor
Description:
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.
CAS:
1415834-63-7
Molecular Weight:
388.80
Formula:
C20H15ClF2N2O2
Chemical Name:
N-(4-((4-chlorobenzyl)oxy)pyridin-2-yl)-2-(2, 6-difluorophenyl)acetamide
Smiles :
O=C(CC1C(F)=CC=CC=1F)NC1=CC(=CC=N1)OCC1C=CC(Cl)=CC=1
InChiKey:
GISJHCLTIVIGLX-UHFFFAOYSA-N
InChi :
InChI=1S/C20H15ClF2N2O2/c21-14-6-4-13(5-7-14)12-27-15-8-9-24-19(10-15)25-20(26)11-16-17(22)2-1-3-18(16)23/h1-10H,11-12H2,(H,24,25,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Donanemab} web|{Donanemab} Amyloid-β|{Donanemab} Technical Information|{Donanemab} In stock|{Donanemab} custom synthesis|{Donanemab} Epigenetics}
Shelf Life:
≥12 months if stored properly.{{Teriflunomide} site|{Teriflunomide} Drug Metabolite|{Teriflunomide} Biological Activity|{Teriflunomide} References|{Teriflunomide} supplier|{Teriflunomide} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24406011
Additional information:
CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor.|Product information|CAS Number: 1415834-63-7|Molecular Weight: 388.80|Formula: C20H15ClF2N2O2|Chemical Name: N-(4-((4-chlorobenzyl)oxy)pyridin-2-yl)-2-(2, 6-difluorophenyl)acetamide|Smiles: O=C(CC1C(F)=CC=CC=1F)NC1=CC(=CC=N1)OCC1C=CC(Cl)=CC=1|InChiKey: GISJHCLTIVIGLX-UHFFFAOYSA-N|InChi: InChI=1S/C20H15ClF2N2O2/c21-14-6-4-13(5-7-14)12-27-15-8-9-24-19(10-15)25-20(26)11-16-17(22)2-1-3-18(16)23/h1-10H,11-12H2,(H,24,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 50 mg/mL (128.60 mM)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|CPDA enhances insulin signaling.|In Vivo:|CPDA greatly improves abnormal glucose metabolism in diabetic animals. CPDA improves the abnormal glucose metabolism in db/db mice.|References:|Rational design and synthesis of 4-substituted 2-pyridin-2-ylamides with inhibitory effects on SH2 domain-containing inositol 5′-phosphatase 2 (SHIP2). Eur J Med Chem. 2013 Apr;62:649-660.Products are for research use only. Not for human use.|
