Product Name :
FGIN-1-27
Description:
FGIN-1-27 is an indoleacetamide that acts as a high affinity agonist of the 18 kDa translocator protein (TSPO; previously called the peripheral benzodiazepine receptor) with a Ki value of 5 nM.1 It can enhance steroidogenesis of neuroactive steroids such as allopregnanolone. Through this action, FGIN-1-27 indirectly potentiates GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and clinical models.
CAS:
142720-24-9
Molecular Weight:
436.60
Formula:
C28H37FN2O
Chemical Name:
2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide
Smiles :
CCCCCCN(CCCCCC)C(=O)CC1C2=CC=CC=C2NC=1C1C=CC(F)=CC=1
InChiKey:
VUWXAQFLTSBUDB-UHFFFAOYSA-N
InChi :
InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{DAPT} site|{DAPT} Organoid|{DAPT} Purity & Documentation|{DAPT} Description|{DAPT} manufacturer|{DAPT} Cancer}
Shelf Life:
≥12 months if stored properly.{{Eltrombopag} MedChemExpress|{Eltrombopag} Immunology/Inflammation|{Eltrombopag} Biological Activity|{Eltrombopag} Purity|{Eltrombopag} supplier|{Eltrombopag} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23659187
Additional information:
FGIN-1-27 is an indoleacetamide that acts as a high affinity agonist of the 18 kDa translocator protein (TSPO; previously called the peripheral benzodiazepine receptor) with a Ki value of 5 nM.1 It can enhance steroidogenesis of neuroactive steroids such as allopregnanolone. Through this action, FGIN-1-27 indirectly potentiates GABAA receptor signaling to produce anticonvulsant, anxiolytic, and sedative activity in both animal and clinical models.|Product information|CAS Number: 142720-24-9|Molecular Weight: 436.60|Formula: C28H37FN2O|Chemical Name: 2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide|Smiles: CCCCCCN(CCCCCC)C(=O)CC1C2=CC=CC=C2NC=1C1C=CC(F)=CC=1|InChiKey: VUWXAQFLTSBUDB-UHFFFAOYSA-N|InChi: InChI=1S/C28H37FN2O/c1-3-5-7-11-19-31(20-12-8-6-4-2)27(32)21-25-24-13-9-10-14-26(24)30-28(25)22-15-17-23(29)18-16-22/h9-10,13-18,30H,3-8,11-12,19-21H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
