5 5 5 Other individuals 2b five 5 99b 5 0b 2b 9b 2b five 99bReaction situations: catalyst 00 mg
5 5 5 Other folks 2b five five 99b five 0b 2b 9b 2b five 99bReaction circumstances: catalyst 00 mg (noble metal four wt ), CyCONH2 0.25 g (two mmol), ,2dimethoxyethane 20 g, H2 8 MPa, 43 K, 24 h. Cy cyclohexyl. Representing loss of carbon balance predominantly through formation of strong solutions around the catalyst surface. Selectivities in these entries are nominal ones because the low conversions preclude obtained information from being comparable with other entries. Mo PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/16123306 three.7 wt . Table 2. Hydrogenation of cyclohexanecarboxamide over Rh oOxSiO2 catalyst many metal oxidesa.Entry two 3 four five six 7aMetal oxide CeO2 ZrO2 TiO2 Al2O3 MgO SiO2 l2O3 HZSM5 NoneConv. CyCH2NH2 89 26 24 6 20 27 34 eight 62 two two 53 39 28 7 49 six 5 5 four 4 5 3Selectivity CyCH2OH (CyCH2)2NH 5 five eight 5 four 26 CyCOOH 
26 20 Othersb 27 37 40 35 42 53 69Reaction situations: Rh oOxSiO2 00 mg (Rh four wt , MoRh ), CyCONH2 0.25 g (2 mmol), metal oxide 00 mg, ,2dimethoxyethane 20 g, H2 eight MPa, 43 K, 4 h. Cy cyclohexyl. b Representing loss of carbon balance predominantly via formation of solid items on the catalyst surface.The catalyst with MoRh eight shows the highest activity in C hydrogenolysis and amino acid hydrogenation. There may perhaps be distinction within the active web sites among amide hydrogenation and these reactions. We selected Rh oOxSiO2 (MoRh ) within the following studies.three.2. Addition of metal oxides to the catalytic program of RhMoOxSiOWe investigated the effects of addition of metal oxides around the catalysis of Rh oOxSiO2 (MoRh ). The outcomes are shown in table 2. The reaction time was set to be shorter than table to compare the activities. The selectivities of RhMoOxSiO2 were nearly the exact same at unique reaction instances (table , entry ; table 2, entry eight). Addition of weakly simple CeO2 and Al2O3 increased the activity (conversion ofsubstrate) and selectivity to CyCH2NH2. The formation of secondary amine ((CyCH2)2NH) was significantly suppressed by the addition. The addition of CeO2 showed the best impact. However, acidic additives such as HZSM5, silicaalumina, ZrO2 and TiO2 showed small effect on the conversion and a great deal decreased the selectivity to CyCH2NH2. Strongly fundamental MgO also decreased the selectivity to CyCH2NH2 and had little effect on the conversion. The selectivity to `others’, which comprised solid polymerized products deposited on the catalyst, was enhanced by addition of acidic or strongly simple oxides. Figure shows the time course of hydrogenation of CyCONH2 over Rh oOxSiO2 in mixture with CeO2. The selectivities have been hardly changed until the total conversion of CyCONH2, then the selectivity to CyCH2NH2 was gradually decreased and that to (CyCH2)2NH wasSci. Technol. Adv. Mater. six (205)Y Nakagawa et alFigure . Time course of hydrogenation of cyclohexanecarboxamide(CyCONH2) more than Rh oOxSiO2 CeO2. Reaction circumstances: RhMoOxSiO2 (Rh 4 wt , MoRh ) 00 mg, CeO2 (uncalcined) 00 mg, ,2dimethoxyethane 20 g, H2 8 MPa, 43 K. Cy cyclohexyl. `Others’ Ansamitocin P 3 comprise unknown solid goods leading to loss of carbon balance for the duration of catalysis.Figure 2. Hydrogenation of cyclohexanecarboxamide (CyCONH2) more than Rh oOxSiO2 several amounts of CeO2. Reaction situations: Rh oOxSiO2 (Rh four wt , MoRh ) 00 mg, CeO2 (uncalcined) 000 mg, ,2dimethoxyethane 20 g, H2 eight MPa, 43 K, 4 h. Cy cyclohexyl. `Others’ comprise unknown strong merchandise major to loss of carbon balance during catalysis.progressively improved. The highest yield of CyCH2NH2 was 63 obtained at eight h (equation (3)). Though the yield worth was decrease tha.
