Product Name :
RITA
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
292.4
Solubility :
Soluble in 100% ethanol (1mg/ml), DMSO (20mg/ml), dimethyl formamide (30mg/ml); 0.5mg/ml soluble in a 1:1 solution of dimethyl formamide: PBS (pH 7.2) (dissolve RITA first in dimethyl formamide and then dilute with PBS).
Appearance:
White to brown crystalline solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stable for at least two years after receipt when stored at -20°C. We do not recommend storing aqueous solutions for more than one day.
Description:
Inhibitor of p53/HDM2 interaction Inhibitor of p53/HDM2 interaction. Activator of p53 function in tumors. Potently inhibits the growth of a variety of cancer cell lines in the submicromolar range.34031-32-8 Formula It has been suggested that RITA selectively targets cells expressing p53 by other mechanisms than direct binding to the N-terminal domain of p53.
CAS :
213261-59-7
Solubility:
Soluble in 100% ethanol (1mg/ml), DMSO (20mg/ml), dimethyl formamide (30mg/ml); 0.5mg/ml soluble in a 1:1 solution of dimethyl formamide: PBS (pH 7.2) (dissolve RITA first in dimethyl formamide and then dilute with PBS).
Formula:
C14H12O3S2
Additional Information :
| Alternative Name Reactivation of p53 and Induction of Tumor Cell Apoptosis, 2,5-bis(5-Hydroxymethyl-2-thienyl)furan, NSC652287 | Appearance White to brown crystalline solid.1852452-14-2 web | CAS 213261-59-7 | Formula C14H12O3S2 | MW 292.PMID:30969528 4 | Purity ≥98% (HPLC) | Solubility Soluble in 100% ethanol (1mg/ml), DMSO (20mg/ml), dimethyl formamide (30mg/ml); 0.5mg/ml soluble in a 1:1 solution of dimethyl formamide: PBS (pH 7.2) (dissolve RITA first in dimethyl formamide and then dilute with PBS). | Unit of Measure (UM) mg
