Product Name :
Mastoparan
Sequence:
H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
Purity:
≥95% (HPLC)
Molecular Weight:
1478.9
Solubility :
Soluble in water (1 mg/ml) or 100% ethanol.
Appearance:
White to off-white solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Store, as supplied, at -20°C for up to 1 year.{{2134641-34-0} medchemexpress|{2134641-34-0} Protocol|{2134641-34-0} Description|{2134641-34-0} custom synthesis} Store solutions at -20°C for up to 3 months.{{51-21-8} MedChemExpress|{51-21-8} Biological Activity|{51-21-8} Purity|{51-21-8} custom synthesis}
Description:
Mast cell degranulating peptide Cell permeable, amphiphilic, mast cell degranulating tetradecapeptide.PMID:29494048 Stimulates glycogenolysis and phospholipase D2 (PLD2) activity. Alters G-proteins in brain membranes. Directly activates G proteins by a mechanism analogous to that of G protein-coupled receptors. Acts preferentially on Gi and Go rather than Gs. Stimulates exocytosis and phosphoinositide breakdown in a variety of cells. Inhibits calmodulin, and activates PLA2. Acts as a mitogen in Swiss 3T3 cells and stimulates pertussis toxin-sensitive arachidonate release without phosphoinositide breakdown.
CAS :
72093-21-1
Solubility:
Soluble in water (1 mg/ml) or 100% ethanol.
Formula:
C70H131N19O15
Additional Information :
| Appearance White to off-white solid. | CAS 72093-21-1 | Formula C70H131N19O15 | Formulation Lyophilized. | Identity Determined by MS. | MW 1478.9 | Purity ≥95% (HPLC) | Sequence H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2 | Solubility Soluble in water (1 mg/ml) or 100% ethanol. | Source Synthetic. Originally isolated from wasp venom (Vespula lewisii).
