Product Name :
SS28
Description:
SS28, a SRT501 analog with oral bioavailability, inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase. SS28 results in apoptosis rather than necrosis tubulin.
CAS:
141172-08-9
Molecular Weight:
284.35
Formula:
C18H20O3
Chemical Name:
1,2,3-trimethoxy-5-[(Z)-2-(4-methylphenyl)ethenyl]benzene
Smiles :
CC1C=CC(=CC=1)/C=C\C1=CC(OC)=C(OC)C(=C1)OC
InChiKey:
YSJFPRSDNPCGBF-KTKRTIGZSA-N
InChi :
InChI=1S/C18H20O3/c1-13-5-7-14(8-6-13)9-10-15-11-16(19-2)18(21-4)17(12-15)20-3/h5-12H,1-4H3/b10-9-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Bumetanide} site|{Bumetanide} NKCC|{Bumetanide} Biological Activity|{Bumetanide} In Vivo|{Bumetanide} manufacturer|{Bumetanide} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SS28, a SRT501 analog with oral bioavailability, inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase. SS28 results in apoptosis rather than necrosis tubulin.|Product information|CAS Number: 141172-08-9|Molecular Weight: 284.35|Formula: C18H20O3|Chemical Name: 1,2,3-trimethoxy-5-[(Z)-2-(4-methylphenyl)ethenyl]benzene|Smiles: CC1C=CC(=CC=1)/C=C\C1=CC(OC)=C(OC)C(=C1)OC|InChiKey: YSJFPRSDNPCGBF-KTKRTIGZSA-N|InChi: InChI=1S/C18H20O3/c1-13-5-7-14(8-6-13)9-10-15-11-16(19-2)18(21-4)17(12-15)20-3/h5-12H,1-4H3/b10-9-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Kaempferol} site|{Kaempferol} Endogenous Metabolite|{Kaempferol} Purity & Documentation|{Kaempferol} Description|{Kaempferol} custom synthesis|{Kaempferol} Autophagy} |Shelf Life: ≥12 months if stored properly.PMID:23812309 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|SS28 (0-20 μM) induces cytotoxicity in different cancer cell lines. SS28 treatment (5 μM for A549 and 2 μM for CEM) results in cell cycle arrest at G2/M phase leading to apoptosis upon further incubation.|In Vivo:|SS28 (15 mg/kg. b.wt.) treatment results in inhibition of tumor cell proliferation.|Products are for research use only. Not for human use.|
