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Product Name :
SPL-410

Description:
SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM.

CAS:
2351886-00-3

Molecular Weight:
500.57

Formula:
C24H31F3N2O4S

Chemical Name:
N-[(2S,3S)-3-amino-2-hydroxy-3-[4-(trifluoromethoxy)phenyl]propyl]-4-tert-butyl-N-cyclobutylbenzene-1-sulfonamide

Smiles :
CC(C)(C)C1C=CC(=CC=1)S(=O)(=O)N(C[C@H](O)[C@@H](N)C1C=CC(=CC=1)OC(F)(F)F)C1CCC1

InChiKey:
KEEHEUGOPCFXAV-VXKWHMMOSA-N

InChi :
InChI=1S/C24H31F3N2O4S/c1-23(2,3)17-9-13-20(14-10-17)34(31,32)29(18-5-4-6-18)15-21(30)22(28)16-7-11-19(12-8-16)33-24(25,26)27/h7-14,18,21-22,30H,4-6,15,28H2,1-3H3/t21-,22-/m0/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.{{Mizoribine} medchemexpress|{Mizoribine} HCV|{Mizoribine} Technical Information|{Mizoribine} Description|{Mizoribine} manufacturer|{Mizoribine} Cancer}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM.{{Alemtuzumab} site|{Alemtuzumab} Apoptosis|{Alemtuzumab} Biological Activity|{Alemtuzumab} In Vivo|{Alemtuzumab} custom synthesis|{Alemtuzumab} Epigenetic Reader Domain} |Product information|CAS Number: 2351886-00-3|Molecular Weight: 500.PMID:25959043 57|Formula: C24H31F3N2O4S|Chemical Name: N-[(2S,3S)-3-amino-2-hydroxy-3-[4-(trifluoromethoxy)phenyl]propyl]-4-tert-butyl-N-cyclobutylbenzene-1-sulfonamide|Smiles: CC(C)(C)C1C=CC(=CC=1)S(=O)(=O)N(C[C@H](O)[C@@H](N)C1C=CC(=CC=1)OC(F)(F)F)C1CCC1|InChiKey: KEEHEUGOPCFXAV-VXKWHMMOSA-N|InChi: InChI=1S/C24H31F3N2O4S/c1-23(2,3)17-9-13-20(14-10-17)34(31,32)29(18-5-4-6-18)15-21(30)22(28)16-7-11-19(12-8-16)33-24(25,26)27/h7-14,18,21-22,30H,4-6,15,28H2,1-3H3/t21-,22-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 190 mg/mL (379.57 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Author: PDGFR inhibitor