Product Name :
HCGRP-(8-37)
Description:
HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor.
CAS:
119911-68-1
Molecular Weight:
3125.59
Formula:
C139H230N44O38
Chemical Name:
N-(1-{[1-({1-[2-({1-[(1-{[1-({[(1-{[5-amino-1-({1-[(1-carbamoyl-2-phenylethyl)carbamoyl]ethyl}carbamoyl)pentyl]carbamoyl}-2-hydroxyethyl)carbamoyl]methyl}carbamoyl)-2-methylpropyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-hydroxypropyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamoyl)-2-phenylethyl]carbamoyl}-2-carbamoylethyl)-2-[6-amino-2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-methylbutanamido)-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido}-5-carbamimidamidopentanamido)-4-methylpentanamido]propanamido}acetamido)-4-methylpentanamido]-4-methylpentanamido}-3-hydroxypropanamido)-5-carbamimidamidopentanamido]-3-hydroxypropanamido}acetamido)acetamido]-3-methylbutanamido}-3-methylbutanamido)hexanamido]butanediamide
Smiles :
CC(C)C(NC(=O)C(CC1C=CC=CC=1)NC(=O)C(CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(NC(=O)CNC(=O)CNC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC1=CNC=N1)NC(=O)C(NC(=O)C(N)C(C)C)C(C)O)C(C)C)C(C)C)C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC1C=CC=CC=1)C(N)=O
InChiKey:
NDACAFBDTQIYCQ-UHFFFAOYSA-N
InChi :
InChI=1S/C139H230N44O38/c1-66(2)48-86(161-102(193)60-155-113(197)74(17)159-120(204)87(49-67(3)4)168-118(202)83(40-31-45-152-138(147)148)163-123(207)90(53-80-57-151-65-158-80)173-136(220)111(77(20)188)182-131(215)105(145)69(7)8)121(205)169-88(50-68(5)6)122(206)176-96(64-186)129(213)165-84(41-32-46-153-139(149)150)119(203)175-94(62-184)115(199)156-58-101(192)154-59-104(195)177-107(71(11)12)134(218)179-108(72(13)14)133(217)166-82(39-28-30-44-141)117(201)171-91(54-98(142)189)125(209)172-92(55-99(143)190)124(208)170-89(52-79-36-25-22-26-37-79)126(210)180-109(73(15)16)137(221)183-47-33-42-97(183)130(214)181-110(76(19)187)135(219)174-93(56-100(144)191)127(211)178-106(70(9)10)132(216)157-61-103(194)162-95(63-185)128(212)164-81(38-27-29-43-140)116(200)160-75(18)114(198)167-85(112(146)196)51-78-34-23-21-24-35-78/h21-26,34-37,57,65-77,81-97,105-111,184-188H,27-33,38-56,58-64,140-141,145H2,1-20H3,(H2,142,189)(H2,143,190)(H2,144,191)(H2,146,196)(H,151,158)(H,154,192)(H,155,197)(H,156,199)(H,157,216)(H,159,204)(H,160,200)(H,161,193)(H,162,194)(H,163,207)(H,164,212)(H,165,213)(H,166,217)(H,167,198)(H,168,202)(H,169,205)(H,170,208)(H,171,201)(H,172,209)(H,173,220)(H,174,219)(H,175,203)(H,176,206)(H,177,195)(H,178,211)(H,179,218)(H,180,210)(H,181,214)(H,182,215)(H4,147,148,152)(H4,149,150,153)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SPP1 Protein, Human (HEK 293, His)} web|{SPP1 Protein, Human (HEK 293, His)} Biological Activity|{SPP1 Protein, Human (HEK 293, His)} Formula|{SPP1 Protein, Human (HEK 293, His)} supplier|{SPP1 Protein, Human (HEK 293, His)} Cancer}
Shelf Life:
≥12 months if stored properly.{{BS3 Crosslinker} site|{BS3 Crosslinker} ADC Linker|{BS3 Crosslinker} Immunology/Inflammation|{BS3 Crosslinker} Technical Information|{BS3 Crosslinker} In stock|{BS3 Crosslinker} supplier}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23812309
Additional information:
HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor.|Product information|CAS Number: 119911-68-1|Molecular Weight: 3125.59|Formula: C139H230N44O38|Chemical Name: N-(1-{[1-({1-[2-({1-[(1-{[1-({[(1-{[5-amino-1-({1-[(1-carbamoyl-2-phenylethyl)carbamoyl]ethyl}carbamoyl)pentyl]carbamoyl}-2-hydroxyethyl)carbamoyl]methyl}carbamoyl)-2-methylpropyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-2-hydroxypropyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamoyl)-2-phenylethyl]carbamoyl}-2-carbamoylethyl)-2-[6-amino-2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-{2-[2-(2-amino-3-methylbutanamido)-3-hydroxybutanamido]-3-(1H-imidazol-4-yl)propanamido}-5-carbamimidamidopentanamido)-4-methylpentanamido]propanamido}acetamido)-4-methylpentanamido]-4-methylpentanamido}-3-hydroxypropanamido)-5-carbamimidamidopentanamido]-3-hydroxypropanamido}acetamido)acetamido]-3-methylbutanamido}-3-methylbutanamido)hexanamido]butanediamide|Smiles: CC(C)C(NC(=O)C(CC1C=CC=CC=1)NC(=O)C(CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(NC(=O)CNC(=O)CNC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(N)=N)NC(=O)C(CC1=CNC=N1)NC(=O)C(NC(=O)C(N)C(C)C)C(C)O)C(C)C)C(C)C)C(=O)N1CCCC1C(=O)NC(C(C)O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC1C=CC=CC=1)C(N)=O|InChiKey: NDACAFBDTQIYCQ-UHFFFAOYSA-N|InChi: InChI=1S/C139H230N44O38/c1-66(2)48-86(161-102(193)60-155-113(197)74(17)159-120(204)87(49-67(3)4)168-118(202)83(40-31-45-152-138(147)148)163-123(207)90(53-80-57-151-65-158-80)173-136(220)111(77(20)188)182-131(215)105(145)69(7)8)121(205)169-88(50-68(5)6)122(206)176-96(64-186)129(213)165-84(41-32-46-153-139(149)150)119(203)175-94(62-184)115(199)156-58-101(192)154-59-104(195)177-107(71(11)12)134(218)179-108(72(13)14)133(217)166-82(39-28-30-44-141)117(201)171-91(54-98(142)189)125(209)172-92(55-99(143)190)124(208)170-89(52-79-36-25-22-26-37-79)126(210)180-109(73(15)16)137(221)183-47-33-42-97(183)130(214)181-110(76(19)187)135(219)174-93(56-100(144)191)127(211)178-106(70(9)10)132(216)157-61-103(194)162-95(63-185)128(212)164-81(38-27-29-43-140)116(200)160-75(18)114(198)167-85(112(146)196)51-78-34-23-21-24-35-78/h21-26,34-37,57,65-77,81-97,105-111,184-188H,27-33,38-56,58-64,140-141,145H2,1-20H3,(H2,142,189)(H2,143,190)(H2,144,191)(H2,146,196)(H,151,158)(H,154,192)(H,155,197)(H,156,199)(H,157,216)(H,159,204)(H,160,200)(H,161,193)(H,162,194)(H,163,207)(H,164,212)(H,165,213)(H,166,217)(H,167,198)(H,168,202)(H,169,205)(H,170,208)(H,171,201)(H,172,209)(H,173,220)(H,174,219)(H,175,203)(H,176,206)(H,177,195)(H,178,211)(H,179,218)(H,180,210)(H,181,214)(H,182,215)(H4,147,148,152)(H4,149,150,153)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: H2O : ≥ 20 mg/mL (6.40 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
