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Product Name :
Teneligliptin hydrobromide hydrate

Description:
Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM.

CAS:
1572583-29-9

Molecular Weight:
637.87

Formula:
C44H67Br5N12O3S2

Chemical Name:
bis(1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazine) hydrate pentahydrobromide

Smiles :
O.{{Axitinib} medchemexpress|{Axitinib} PDGFR|{Axitinib} Technical Information|{Axitinib} In Vivo|{Axitinib} custom synthesis|{Axitinib} Autophagy} Br.Br.Br.Br.Br.CC1C=C(N(N=1)C1C=CC=CC=1)N1CCN(CC1)[C@H]1C[C@H](NC1)C(=O)N1CSCC1.CC1C=C(N(N=1)C1C=CC=CC=1)N1CCN(CC1)[C@H]1C[C@H](NC1)C(=O)N1CSCC1

InChiKey:
NQPRXLXVOBOTGT-KSLCDFCZSA-N

InChi :
InChI=1S/2C22H30N6OS.5BrH.H2O/c2*1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27;;;;;;/h2*2-6,13,19-20,23H,7-12,14-16H2,1H3;5*1H;1H2/t2*19-,20-;;;;;;/m00……/s1

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
Teneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM.{{Diosmin} MedChemExpress|{Diosmin} Immunology/Inflammation|{Diosmin} Technical Information|{Diosmin} References|{Diosmin} custom synthesis|{Diosmin} Autophagy} |Product information|CAS Number: 1572583-29-9|Molecular Weight: 637.PMID:23962101 87|Formula: C44H67Br5N12O3S2|Chemical Name: bis(1-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-4-[(3S,5S)-5-(1,3-thiazolidine-3-carbonyl)pyrrolidin-3-yl]piperazine) hydrate pentahydrobromide|Smiles: O.Br.Br.Br.Br.Br.CC1C=C(N(N=1)C1C=CC=CC=1)N1CCN(CC1)[C@H]1C[C@H](NC1)C(=O)N1CSCC1.CC1C=C(N(N=1)C1C=CC=CC=1)N1CCN(CC1)[C@H]1C[C@H](NC1)C(=O)N1CSCC1|InChiKey: NQPRXLXVOBOTGT-KSLCDFCZSA-N|InChi: InChI=1S/2C22H30N6OS.5BrH.H2O/c2*1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27;;;;;;/h2*2-6,13,19-20,23H,7-12,14-16H2,1H3;5*1H;1H2/t2*19-,20-;;;;;;/m00……/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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Author: PDGFR inhibitor