Product Name :
Cinepazide Maleate
Description:
Cinepazide Maleate is a maleate salt form of cinepazide which is a vasodilator
CAS:
26328-04-1
Molecular Weight:
533.57
Formula:
C26H35N3O9
Chemical Name:
1-[(1-Pyrrolidinylcarbonyl)methyl]-4-(3,4,5-trimethoxycinnamoyl)piperazine Maleate
Smiles :
COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1.OC(=O)/C=C\C(O)=O
InChiKey:
XSTJTOKYCAJVMJ-GVTSEVKNSA-N
InChi :
InChI=1S/C22H31N3O5.C4H4O4/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24;5-3(6)1-2-4(7)8/h6-7,14-15H,4-5,8-13,16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b7-6+;2-1-
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cinepazide Maleate is a maleate salt form of cinepazide which is a vasodilator|Product information|CAS Number: 26328-04-1|Molecular Weight: 533.{{Zoledronic Acid} site|{Zoledronic Acid} Apoptosis|{Zoledronic Acid} Technical Information|{Zoledronic Acid} Data Sheet|{Zoledronic Acid} custom synthesis|{Zoledronic Acid} Cancer} 57|Formula: C26H35N3O9|Synonym:|MD-67350|Related CAS Number:|23887-46-9 (free base)|88197-48-2 (mesylate)|Chemical Name: 1-[(1-Pyrrolidinylcarbonyl)methyl]-4-(3,4,5-trimethoxycinnamoyl)piperazine Maleate|Smiles: COC1C=C(C=C(OC)C=1OC)/C=C/C(=O)N1CCN(CC(=O)N2CCCC2)CC1.OC(=O)/C=C\C(O)=O|InChiKey: XSTJTOKYCAJVMJ-GVTSEVKNSA-N|InChi: InChI=1S/C22H31N3O5.{{Natamycin} MedChemExpress|{Natamycin} Metabolic Enzyme/Protease|{Natamycin} Technical Information|{Natamycin} Data Sheet|{Natamycin} supplier|{Natamycin} Autophagy} C4H4O4/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24;5-3(6)1-2-4(7)8/h6-7,14-15H,4-5,8-13,16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b7-6+;2-1-|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (187.PMID:23776646 42 mM; Need ultrasonic) H2O : 50 mg/mL (93.71 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Cinepazide Maleate (intravenous injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects[1]. Cinepazide Maleate (intravertebral injection; 1-10 mg/kg) increases vertebral blood flow in a dose-related manner and the effect is partially inhibited by Aminophylline (HY-B0140) in dogs[1].|References:|Akashi, A., et al., [Cardiovascular pharmacology of cinepazide, a new cerebral vasodilator (author’s transl)]. Nihon Yakurigaku Zasshi, 1979. 75(5): p. 507-16.Jun Ni , et al. Efficacy and safety of cinepazide maleate injection in patients with acute ischemic stroke: a multicenter, randomized, double-blind, placebo-controlled trial. BMC Neurol. 2020 Jul 14;20(1):282.Products are for research use only. Not for human use.|
