Product Name :
PC-Biotin-PEG4-NHS carbonate
Description:
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2055198-03-1
Molecular Weight:
810.87
Formula:
C35H50N6O14S
Chemical Name:
1-{5-[(1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-3,6,9,12-tetraoxapentadecan-15-amido)methyl]-2-nitrophenyl}ethyl 2,5-dioxopyrrolidin-1-yl carbonate
Smiles :
CC(OC(=O)ON1C(=O)CCC1=O)C1=CC(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)=CC=C1[N+]([O-])=O
InChiKey:
APFWBUQXFFFWPE-WMEVZKCTSA-N
InChi :
InChI=1S/C35H50N6O14S/c1-23(54-35(47)55-40-31(44)8-9-32(40)45)25-20-24(6-7-27(25)41(48)49)21-37-30(43)10-12-50-14-16-52-18-19-53-17-15-51-13-11-36-29(42)5-3-2-4-28-33-26(22-56-28)38-34(46)39-33/h6-7,20,23,26,28,33H,2-5,8-19,21-22H2,1H3,(H,36,42)(H,37,43)(H2,38,39,46)/t23?,26-,28-,33-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2055198-03-1|Molecular Weight: 810.87|Formula: C35H50N6O14S|Chemical Name: 1-{5-[(1-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}-3,6,9,12-tetraoxapentadecan-15-amido)methyl]-2-nitrophenyl}ethyl 2,5-dioxopyrrolidin-1-yl carbonate|Smiles: CC(OC(=O)ON1C(=O)CCC1=O)C1=CC(CNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)=CC=C1[N+]([O-])=O|InChiKey: APFWBUQXFFFWPE-WMEVZKCTSA-N|InChi: InChI=1S/C35H50N6O14S/c1-23(54-35(47)55-40-31(44)8-9-32(40)45)25-20-24(6-7-27(25)41(48)49)21-37-30(43)10-12-50-14-16-52-18-19-53-17-15-51-13-11-36-29(42)5-3-2-4-28-33-26(22-56-28)38-34(46)39-33/h6-7,20,23,26,28,33H,2-5,8-19,21-22H2,1H3,(H,36,42)(H,37,43)(H2,38,39,46)/t23?,26-,28-,33-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{RGX-202} MedChemExpress|{RGX-202} Endogenous Metabolite|{RGX-202} Purity & Documentation|{RGX-202} Formula|{RGX-202} supplier|{RGX-202} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Docosahexaenoic Acid} MedChemExpress|{Docosahexaenoic Acid} Metabolic Enzyme/Protease|{Docosahexaenoic Acid} Biological Activity|{Docosahexaenoic Acid} In Vivo|{Docosahexaenoic Acid} custom synthesis|{Docosahexaenoic Acid} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23891445 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
