Ript NIH-PA Author Manuscript NIH-PA Author ManuscriptDev Biol. Author manuscript; offered in PMC 2008 December 1.Cook et al.PageTwo days before prostatic bud initiation, the E14 Noggin-/- UGS showed diminished ventral mesenchymal cell Insulin-like Growth Factor I (IGF-1) Proteins Recombinant Proteins density relative towards the age-matched WT UGS (Fig. 4A, appropriate column, outlined in pink), that is consistent with impaired ventral mesenchymal pad formation observed on P1. The decreased ventral mesenchymal cell density at E14 was